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KMID : 0191120130280010152
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Journal of Korean Medical Science
2013 Volume.28 No. 1 p.152 ~ p.155
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An Adult Case of Fisher Syndrome Subsequent to Mycoplasma pneumoniae Infection
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Lee So-Yeon
Lee Yong-Hoon
Chun Bo-Young
Lee Shin-Yup
Cha Seung-Ick
Kim Chang-Ho
Park Jae-Yong
Lee Jae-Hee
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Abstract
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Reported herein is an adult case of Fisher syndrome (FS) that occurred as a complication during the course of community-acquired pneumonia caused by Mycoplasma pneumoniae. A 38-yr-old man who had been treated with antibiotics for serologically proven M. pneumoniae pneumonia presented with a sudden onset of diplopia, ataxic gait, and areflexia. A thorough evaluation including brain imaging, cerebrospinal fluid examination, a nerve conduction study, and detection of serum anti-ganglioside GQ1b antibody titers led to the diagnosis of FS. Antibiotic treatment of the underlying M. pneumoniae pneumonia was maintained without additional immunomodulatory agents. A complete and spontaneous resolution of neurologic abnormalities was observed within 1 month, accompanied by resolution of lung lesions.
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KEYWORD
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Mycoplasma pneumoniae, Fisher Syndrome, Anti-GQ1b Antibody
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